Bilirubin metabolism and Jaundice
Bilirubin synthesis Bilirubin is a yellow or orange colored pigment derived from heme. After about 120 days RBCs undergo hemolysis to give hemoglobin. This hemoglobin is converted to heme and globin. Heme undergoes further degradation by heme oxygenase to give green colored pigment biliverdin and iron in the form of ferric ion. This particular…